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TRANSIL AGP Binding Kit

A ready-to-use kit for rapid assessment of drug candidates' binding a1-acid glycoprotein (AGP) plasma protein

A novel ready-to-use binding kit designed to assess the binding of drugs to plasma binding protein and mimic the physiological condition of the major plasma protein a1-acid glycoprotein (AGP). The affinity of a drug candidate to plasma proteins is a true measurement of the free fraction of a drug candidate in plasma.

Benefits

  • Fast, requiring only 2 minutes for incubation.
  • Accurate. Measures the affinity of the drug candidate to a1-acid glycoprotein (AGP) a true measurement of the free fraction in plasma, capable of producing pharmacological effects.
  • Reliable with highly reproducible results.
  • Ready-to-use format plated in 96-well or ready-to-use tubes in strips of 8. Kit only requires addition of test material, 2-minute incubation, and quantification.
  • Flexible. Enables physiology based modeling (e.g Simcyp) by providing affinity input data. Format is adaptable to automation.

Product Information

 

Product Number Product Name Format
TPB-0211-0096 Transil AGP Binding Kit 96-well plate
TPB-0211-1196 Transil AGP Binding Kit 96-well (strips)

 

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